ד"ר שרון פליישר

The Fleischer Lab pioneers next-generation organ-on-a-chip technologies to advance human health and precision medicine. By integrating human stem cells, complex biomaterials, and advanced bioreactors, we build miniature organs that capture human physiology and disease. Our goal is to uncover fundamental mechanisms of human (patho)physiology and translate these insights into new diagnostic and therapeutic strategies. Furthermore, we leverage these human models as predictive testbeds for drug screening and the discovery of new therapies

Current research directions in the lab include:

(1) Engineering human models of autoimmune-mediated cardiac diseases to improve patient diagnosis and treatment.

(2) Developing 4D hearts-on-a-chip models of cardiac circadian rhythms to understand how time-of-day shapes cardiac health and affects drug efficacy.

(3) Engineering patient-specific neuromuscular junction models of spinal muscular atrophy (SMA) to uncover disease mechanisms and accelerate drug discovery.

(4) Designing advanced biomaterials and engineered tissues to study cardiac aging and regeneration.

We are an interdisciplinary, highly collaborative lab seeking curious and motivated Master’s students, Ph.D. candidates, and postdoctoral fellows who are excited to push the boundaries of human tissue engineering and translational bioengineering