פרופ' אורן קובילר

1996-2007 - לימודים לתואר דוקטור לרפואה/ לפילוסופיה, M.D./Ph.D. האוניברסיטה העברית ירושלים.

 

2007-2012 - פוסט דוקטוראט, אוניברסיטת פרינסטון, פרינסטון, ניו-ג'רסי. 

 

2012-2022 - מרצה בכיר, המחלקה למיקרוביולוגיה ואימונולוגיה קלינית, סאקלר, אוניברסיטת תל אביב.

2022 -היום - פרופסור חבר, המחלקה למיקרוביולוגיה ואימונולוגיה קלינית, סאקלר, אוניברסיטת תל אביב.

 

 

 

 

אנחנו חוקרים נגיפים ממשפחת ההרפס, בדגש על נגיף ההרפס סימפלקס -1.

 

 

 

 

 

 

 

A Single Herpes Simplex Virus 1 Genome Reactivates from Individual Cells 2022

D Rafael, E Tomer, O Kobiler

Microbiology Spectrum 10 (4), e01144-22

 

Insular cortex neurons encode and retrieve specific immune responses 2021

T Koren, M Amer, M Krot, N Boshnak, TL Ben-Shaanan, H Azulay-Debby, ...

Cell 184 (24), 5902-5915. e17

 

Multi-clonal SARS-CoV-2 neutralization by antibodies isolated from severe COVID-19 convalescent donors 2021

M Mor, M Werbner, J Alter, M Safra, E Chomsky, JC Lee, S Hada-Neeman, ...

PLoS pathogens 17 (2), e1009165

 

The fate of incoming HSV-1 genomes entering the nucleus 2021

O Kobiler, A Afriat

Current Issues in Molecular Biology 41 (1), 221-266

 

Conserved interactions required for inhibition of the main protease of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 2020

A Shitrit, D Zaidman, O Kalid, I Bloch, D Doron, T Yarnizky, I Buch, I Segev, ...

Scientific reports 10 (1), 1-11

 

Abortive herpes simplex virus infection of nonneuronal cells results in quiescent viral genomes that can reactivate 2020

EM Cohen, N Avital, M Shamay, O Kobiler

Proceedings of the National Academy of Sciences 117 (1), 635-640

 

Coalescing replication compartments provide the opportunity for recombination between coinfecting herpesviruses 2019

E Tomer, EM Cohen, N Drayman, A Afriat, MD Weitzman, A Zaritsky, ...

The FASEB journal 33 (8), 9388-9403

 

Herpes simplex virus replication compartments: From naked release to recombining together 2019

O Kobiler, MD Weitzman

PLoS pathogens 15 (6), e1007714

 

Dynamic proteomics of herpes simplex virus infection 2017

N Drayman, O Karin, A Mayo, T Danon, L Shapira, D Rafael, A Zimmer, ...

MBio 8 (6), e01612-17

 

Promoting simultaneous onset of viral gene expression among cells infected with herpes simplex virus-1 2017

M Ralph, M Bednarchik, E Tomer, D Rafael, S Zargarian, M Gerlic, ...

Frontiers in Microbiology 8, 2152

 

Gene expression correlates with the number of herpes viral genomes initiating infection in single cells 2016

EM Cohen, O Kobiler

PLoS pathogens 12 (12), e1006082       

 

Histone deacetylase inhibitors reduce the number of herpes simplex virus-1 genomes initiating expression in individual cells 2016

L Shapira, M Ralph, E Tomer, S Cohen, O Kobiler

Frontiers in microbiology 7, 1970

 

Vaccination strategies against respiratory syncytial virus 2016

D Yamin, FK Jones, JP DeVincenzo, S Gertler, O Kobiler, JP Townsend, ...

Proceedings of the National Academy of Sciences 113 (46), 13239-13244            

 

A ‘tool box’for deciphering neuronal circuits in the developing chick spinal cord 2014

Y Hadas, A Etlin, H Falk, O Avraham, O Kobiler, A Panet, A Lev-Tov, ...

Nucleic acids research 42 (19), e148-e148

 

Virus strategies for passing the nuclear envelope barrier 2012

O Kobiler, N Drayman, V Butin-Israeli, A Oppenheim

Nucleus 3 (6), 526-539

 

Alphaherpesvirus axon-to-cell spread involves limited virion transmission 2012

MP Taylor, O Kobiler, LW Enquist

Proceedings of the National Academy of Sciences 109 (42), 17046-17051