We develop noninvasive medical ultrasound technologies for diagnostics, monitoring, and therapy for clinically relevant problems. Our research is highly multidisciplinary, combining engineering, physics, biology, chemistry and medicine. We utilize the unique ability of sound waves to penetrate deep into the body, in some cases even through an intact skull, and couple it with gas-bubbles. These bubbles are efficient theranostic probes that can be used for simultaneous imaging and controlled therapy at a targeted site. We develop enhanced ultrasound-mediated gene delivery methods, noninvasive ultrasound surgery, and safe and precise blood brain barrier opening for brain therapy. In parallel, we are developing optically-inspired ultrasonic techniques for overcoming current limitations in ultrasound imaging. Current interests include 3D ultrasound, super-resolution, image processing and machine learning.
ד"ר טלי אילוביץ
Research Interests
Curriculum Vitae
Since 2019 Senior Lecturer (Assistant Professor aquivalent)
Department of Biomedical Engineering, Tel Aviv University, Israel
2018-2019 Postdoctoral Fellow, Stanford University, USA
Department of Radiology, School of Medicine, Stanford University, Stanford, California, USA
2016-2018 Postdoctoral Fellow, University of California at Davis, USA
Department of Biomedical Engineering, Faculty of Engineering, University of California at Davis, Davis, California, USA
2012-2016 Ph.D. Electrical Engineering
Department of Electrical Engineering, Faculty of Engineering, Bar Ilan University, Israel.
2010-2012 M.Sc. Electrical Engineering
Department of Electrical Engineering, Faculty of Engineering, Bar Ilan University, Israel.
2007-2011 B.Sc. Electrical Engineering
Department of Electrical Engineering, Faculty of Engineering, Bar Ilan University, Israel.
תחומי מחקר
פיתוח טכנולוגיות חדשות בתחום האולטרסאונד הרפואי. הדמיית אולטרסאונד בתלת מימד, סופר-רזולוציה, עיצוב חזית הגל, עיבוד תמונה, ולמידת מכונה. אולטרסאונד טיפולי בשילוב עם מיקרו-בועות לצורך העברת תרופות, ריפוי גני, פתיחת מחסום הדם-מוח, אבלציות מכניות ותרמיות.
Selected publications
T. Ilovitsh, et al. "Low-frequency ultrasound-mediated cytokine transfection enhances T cell recruitment at local and distant tumor sites." Proceedings of the National Academy of Sciences (2020).
T. Ilovitsh, A. Ilovitsh, J. Foiret, C.F. Caskey, J. Kusunose, B.Z. Fite, H. Zhang, L.M. Mahakian, S. Tam, K. Butts-Pauly, S. Qin, and K.W. Ferrara, “Enhanced microbubble contrast agent oscillation following 250 kHz insonation”. Scientific Reports, 8, 1-15 (2018).
T. Ilovitsh, A. Ilovitsh, J. Foiret and K.W. Ferrara, “Imaging beyond ultrasonically-impenetrable objects”. Scientific Reports, 8, 575901-575911 (2018).
T. Ilovitsh, A. Ilovitsh, J. Foiret, B.Z. Fite and K.W. Ferrara, "Acoustical structured illumination for super-resolution ultrasound imaging". Communications Biology, 1, 1-11 (2018).
T. Ilovitsh, A. Ilovitsh, A. Weiss, R. Meir and Z. Zalevsky, "Three dimensional imaging of gold-nanoparticles tagged samples using phase retrieval with two focus planes". Scientific Reports, 5, 154731-154739 (2015).
T. Ilovitsh, A. Weiss, A. Meiri, C. G. Ebeling, A. Amiel, H. Katz, B.M. Green and Z. Zalevsky, "K-factor image deshadowing for three-dimensional fluorescence microscopy". Scientific Reports, 5, 137241- 1372410 (2015).
