June 2025:

• Warm congratulations to Yann on the publication of his paper on ZC3H4 in Science Advances.

March 2025:

• Our lab took part in the Departmental retreat which was held this time in Jerusalem. Yann Frey presented his work in an excellent talk, as one of the winners of the Departmental Research Excellence Award for 2025. Photo gallery here.


• Congratulations to our graduate student Yann Frey on winning the Best Poster Prize in the Israeli RNA Biology Meeting of 2025 which was held this year at Ben-Gurion University.

January 2025:

• Congratulations to Dr. Sharone Naor on the publication of his paper in JoVE on Visualizing the DNA Damage Response in Purkinje Cells Using Cerebellar Organotypic Cultures


• We are proud of our PhD student Yann Frey for receiving our Department's Prize of Excellence in Research Scholarships. The committee has decided to award Yann the Second prize as Outstanding Departmental researcher for the year 2024. Chair: Prof. Ruth Ashery- Padan


• Congratulations to Majd on the publication of his paper, "The cGAS–STING, p38 MAPK, and p53 pathways link genome instability to accelerated cellular senescence in ATM-deficient murine lung fibroblasts" in PNAS!

December 2024:

• Congratulations to Yann on the publication of his paper, "Broad repression of DNA repair genes in senescent cells identified by integration of transcriptomic data" in Nucleic Acids Research!

September 2024:

• Congratulations to Yann on a great talk at the Jacques Monod Conference on Transcription and Genome Stability, which took place in Roscoff, France. Photo here.


• Hearty congratulations to our Graduate student Yann Frey for winning the 6th Esther and Zvi Weinstat Memorial Graduate Award in Cancer Research, awarded by the Cancer Biology Research Center of Tel Aviv University "for notable achievements in cancer research". Yann, along with several other graduate students from the Faculties of Medicine and Life Sciences, has earned this prestigious award for 2024.

June 2024:

• On June 10th, our graduate student Yann Frey presented an excellent Departmental Seminar on his two main projects, both involving senescense. The presentation was very well received as can be seen in the photos here.


• We are proud to annouce that Dr. Majd Haj has officially been given the title Doctor of Philosophy after the approval of his graduate thesis. Hearty congratulations from your fellow lab members! Here are photos from the farewell party.

April 2024:

• Congratulations! Yossi is now an official member of the National Academy of Sciences. Watch the recording of the Presentation Ceremony for Members Elected in 2023 at the NAS 161st Annual Meeting. Go to 57:10 to see Yossi. Photo here

February 2024:

• Our graduate student Majd Haj won first prize for the best poster presentation at the Genetic Society Annual Meeting at the Weizmann Institute of Science. Well Done! Photo album here

• Hearty congratulations to Dr. Sharone Naor on the approval of his PhD thesis. Sharone’s work met several challenges and took him into many experimental arenas. It made a significant step forward in our understanding the cerebellar degeneration in A-T.

January 2024:

• We welcome Yann Frey back to the lab after having spent 6 months performing experiments and learning techniques at the NYU School of Medicine's Department of Biochemistry.

June 2023:

• Congratulations again to Majd, Yann and Yael – the “human” senescence paper is out in Aging Cell. Link to paper

May 2023:

• National Academy of Sciences of the United States elects Prof. Yosef Shioh as an International Member. Link to the announcement

April 2023:

• Congratulations to Majd, Yann and Yael on the acceptance of their paper to Aging Cell.

March 2023:

• Yossi spoke at the "White Coats" demonstration against abolishing democracy in Israel. Video here
• Majd gave a talk at the 2023 A-T Workshop (ATW2023) in Kyoto, Japan

November 2022:

• Our graduate student, Majd Haj, gave an impressive lecture at the Minerva Workshop on Metabolism and Ageing. His talk was about the link between genome instability and cell senescence, which is convincingly demonstrated in ataxia-telangiectasia.

October 2022:

• Congratulations to our Graduate Students Majd Haj and Yann Frey, for winning the 2nd Prize for Best Poster at the Annual Meeting of the International Cell Senescence Association (ICSA), held in Groningen, Netherlands.

August 2022:

• We welcome our new Research Associate, Ami Nehaisy to our team.

July 2022:

• Abeer Saeed was accepted to the Graduate Research Program of the Sagol School of Neuroscience. We wish her much success in her Graduate studies.

June 2022:

• Our Graduate Student, Yann Frey, presented his work at the Annual Meeting of the HealthAge ITN Consortium, in Crete.

May 2022:

• We welcomed Dr. Yael Ziv, our Senior Staff Scientist who has returned to the lab.

December 2021:

• We said farewell this month to Dr. Kenneth Hollander who has accepted a position in the University grants office, and we thank him for his devoted work over the years.

November 2021:

• Dr. Yael Ziv, our Senior Staff Scientist, has retired after 36 unforgettable years in the Shiloh lab, ever since its establishment in 1985. We were honored to gather together many of our lab's graduates from over the years, in ordetr to celebrate her immense contribution to science. Photos from the special event can be viewed in this album

October 2021:

• This month we welcome a new Research Associate, Abeer Saeed, who will be working on mouse models of premature aging.

May 2021:

• At the end of May we bade farewell to two fantastic graduate students: Megi Cemel-David and Marina Alfo. Wishing them both much success in their future endeavors! Photo album here

Febuary 2021:

• An author commentary about Sapir's paper was published in the journal Molecular and Cellular Oncology.

January 2021:

• Congratualtions to Sapir Schlam-Babayov on the publication of her phosphoproteomic work in the EMBO Journal.
• Congratulations to Megi Cemel-David on the approval of her Ph.D. thesis, titled "Characterization of the dynamics and function of the ubiquitin E3 ligase, CRL4, in the cellular response to double-strand breaks in the DNA".

September 2020:

• Yossi's comprehensive review on "The cerebellar degeneration in ataxia-telangiectasia" came out in DNA Repair.

May 2020:

• In April & May we welcomed two new babies to the lab's "extended family". We wish a warm Congratulations to Megi and Mikki, on the birth of Mila, younger sister to sweet Maya, and also to Marina and Itai on the birth of Lia, younger sister to sweet Sophie! Wishing both families much health and happiness.
• In May Yossi gave a webinar in the DNA Repair Interest Group of the NIH, on the topic, "What has ATM taught us so far about ataxia-telangiectasia?" The seminar can be viewed at https://videocast.nih.gov/watch=34929

December 2019:

• Yossi returned from a useful and enjoyable Sabbatical at Rockefeller University in New York, having spent 4 months there.

November 2019:

• We warmly welcome Yann Frey, a PhD student from France who will be taking part in our Ageing project with a prestigious Marie Curie fellowship.
• We bade farewell to Juliya Ben-Oded who was part of our dedicated mouse team. We wish her much luck in her future directions.

September 2019:

• Congratulations to Efrat Tal on the approval of her PhD thesis on "Investigation of ATM function in the cerebellum using genetic mouse models".
• Sapir and her family departed for the USA: new location, new horizons. Farewell and best wishes for success and happiness!

August 2019:

• We bade farewell to Dhananjay after completing his Post-Doctoral training in our lab. Wishing him success in his new lab in Sweden!

July 2019:

• Our Graduate student Sapir Babayov-Schalmm will soon be embarking on a new adventure across the sea. We got together for a tasty feast to wish her and her family a warm farewell. Photos album here.
• We also said goodbye to our dear friend Jonathan Aran, who worked as a Lab Technologist with our mouse team for the past two years. Wishing him all the best for the future!

June 2019:

• Congratulations to our Graduate Student Majd Haj on his being accepted to the next Roche Continents Seminar. Majd is one of 100 students from around the world chosen to attend the seminar in Salzburg, Austria in August 2019.

March 2019:

• Hearty congratulations to Julia and Ronen on the birth of their firstborn daughter Mika! A big Mazal Tov from all of us in the lab.

January 2019:

• Our paper describing the protein UBQLN4 as a new factor in maintaining genome stability came out in Cell. Hearty congratulations to everybody in our lab who was involved: Ron, who led the project; Yael, who guided Ron and made it possible to initiate the project and carry out its first phase, in our lab; Bhavana who contributed experimental work;ֲ  Keren, in whose screen UBQLN came up, and Nizan, for the meta-analysis work. Well done to you all!
• Our UBQLN4 story was highlighted in the Walla News portal.

September 2018:

• Congratulations to Efrat on the publication of her paper "Inactive Atm abrogates DSB repair in mouse cerebellum more than does Atm loss, without causing a neurological phenotype" in DNA Repair. Great thesis paper!

August 2018:

• This month we welcomed a new baby to the world and we send hearty congratulations to Sapir and Ophir Shalem on the birth of their first baby boy, Eitan.
• We also bade farewell to Efrat Tal who has completed her studies and submitted her paper on the DNA damage response in the nervous system. Photos from the party can be found in this album.

July 2018:

• Hearty congratulations to Majd on being awarded a highly prestigious fellowship by the Council of Higher Education. 14 such fellowships are awarded to Arab doctoral students — for the entire country in ALL academic disciplines. Great achievement!!
• Congratulations again to Majd, this time for being awarded a prize for his poster presentation at the 2018 Cellular Senescence Meeting in Montreal, Canada. This is a great achievement for Majd and also for our lab, since we're essentially newcomers to the cell senescence field.

June 2018:

• Congratulations to Majd for being awarded the Constantiner Travel Award to attend the Annual Meeting of the International Cell Senescence Association in Montreal in July. Majd will present a poster about his work.

May 2018:

• At the end of May our lab had a fun and educational excursion together. We toured the old city of Akko and saw the unique natural beauty of the grottoes at Rosh Hanikra.
  Photo album here.

March 2018:

• Congratulations to Keren on the publication of her paper "The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair", in Molecular Cell. It was a long journey, with lots of hard work put in by all those involved. Well done!
• A very warm Mazal Tov to Sharone and Lital on the birth of their beautiful daughter, Gili, sister to Eden.

February 2018:

• We are pleased to welcome Dr. Dhananjay K. Singh, who is joining us from India for his post-doctoral studies. Welcome to Israel!

November 2017:

• Congratulations to Michal Gavish Izakson, Yael and Bhavana, on the acceptance of their paper on the protein PABPN1 — a new player in the DNA damage response, for publication in Nucleic Acids Research.

October 2017:

• Mazal Tov to Marina and her husband, Ittai, on the birth of their firstborn baby daughter Sophie!
• We welcome Dean Ariel who is joining us to pursue his PhD thesis in the framework of the MD/PhD program.

September 2017:

• We welcome Jonathan Aran who is joining our lab as a lab technologist studying the cerebellar degeneration in A-T.

July 2017:

• This month we welcome Jennifer Pastor to our team. She will be working on the genome stability-aging link.

June 2017:

• On 18.6 we bade farewell to Nataly Kaminsky who completed a joint PhD thesis with the lab of Prof. Ari Barzilai. Here are photos from her tasty farewell party. 

• Best wishes to Majd Haj of our group who is heading off to visit the lab of Prof. Judith Campisi at the Buck Institute for Research on Aging in California. Majd will carry out experiments there, related to a joint project of the two labs on the link between genome instability, aging and cell senescence. 

May 2017:

• A big Mazal Tov to Megi and Mickey, new proud parents of sweet little Maya!

• Kudos to Marina Alfo and Sapir Schlamm for representing us so well in the departmental seminar.

April 2017:

• To mark the beginning of Spring, our lab went on a wonderful and refreshing Day Trip, to see the ancient city of Beit She'an and to take in the beautiful sights of the Gilboa. Photos can be viewed in this album. 

• Our lab participated in the annual Israeli Genome Stability meeting hosted this year at Bar-Ilan University. Congratulations to Michal and Sapir on their great poster presentations, and special congratulations to Michal for getting the 2nd prize for best poster!!