Prof. Tal Pupko

Tal Pupko - Research interests Tal Pupko - Research interests :


My research interests are concerned with various fields of Molecular Evolution and Bioinformatics:

Molecular evolution: studying the evolutionary selective forces shaping genes and genomes and the in-silico predictions of these forces using probabilistic evolutionary models

Phylogenetics: reconstructing evolutionary relationships and ancestral sequences, inferring lateral gene transfer, alignment and alignment reliability.

Pathogenomics: developing and applying machine-learning tools for predicting effector proteins in pathogenic bacteria such as Legionella and Coxiella. Predicting hydrogenosomal proteins in Trichomonas vaginalis. Functional and evolutionary analysis of HIV-1 genomes.

Immunoformatics: predicting B cell epitopes and developing algorithms for analyzing phage display experiments.