Laboratory of Cardiovascular Biology

Heads of Laboratory: Ran Kornowski M.D and Eli Lev, M.D.

	Tel:	972-3-9376481
	Fax:	972-3-9249850
	E-mail:	rkornowski@clalit.org.il, Elil@clalit.org.il

Research Topics

1. The effect of intensive glycemic control on endothelial progenitor cells level and function in patients with diabetes

2. Exposure to platelets affects the function of endothelial progenitor cells

3. Circulating endothelial progenitor cells Level and function in patients with bicuspid aortic valve

4. Circulating endothelial progenitor cells levels and function in patients who suffered late coronary stent thrombosis event

5. Effect of high dose statin pretreatment on endothelial progenitor cells and circulating endothelial cells after percutaneous coronary intervention

6. Factors mediating the effects of platelets on functional capacity and differentiation of endothelial progenitor cells (EPCs)

Selected Publications

1. Raiter A, Bechor Z, Kleiman M, Leshem-Lev D, Battler A, Hardy B. Angiogenic peptides improve blood flow and promote capillary growth in a diabetic and ischaemic mouse model. Eur J Vasc Endovasc Surg. 40(3):381-388.2010. MEDLINE

2. Lev EI, Leshem-Lev D, Mager A, Vaknin-Assa A, Harel N, Zimra Y, Bental T, Greenberg G, Dvir D, Assali A, Battler A, Kornowski R. Circulating endothelial progenitor cells levels and function in patients who experienced late coronary stent thrombosis. European Heart Journal 31(21):2625-2632, 2010 MEDLINE

3. Leshem-Lev D, Omelchenko A, Perl L, Kornowski R, Battler A, Lev EI. Exposure to platelets promotes functional properties of endothelial progenitor cells. J Thromb Thrombolysis. 30(4):398-403, 2010. MEDLINE

4. Vaturi M, Perl L, Leshem-Lev D, Dadush O, Bental T, Shapira Y, Yedidya I, Greenberg G, Kornowski R, Sagie A, Battler A, Lev EI. Circulating endothelial progenitor cells in patients with dysfunctional versus normally functioning congenitally aortic valves. Am J Cardiol. 108(2):272-6, 2011. MEDLINE

5. Lev EI, Zinger J, Leshem-Lev D, Rigler M, Dadush O, Battler A, Kornowski R. Endothelial progenitor cells in patients with long-standing uncontrolled diabetes: effect of intensive glycemic control. European Journal of Preventive Cardiology (2013), Submitted.