Welcome to our lab!
Our main research interests are concerned with the broad field of plant evolution and phylogenetics. We use comparative, bioinformatics approaches to gain insights into the fascinating evolutionary dynamics of plant genomes. In this process, we develop novel computational tools, based on machine learning, reinforcement learning, and advanced probabilistic evolutionary models. These allow us to gain novel biological insights from various kinds of data. For more detailed information see the Research page.
Josef re-joins the lab as our web-master. Keep them running Josef.
Fighting COVID. We show that the response time is more important than lockdown strictnesss. Read it here Read it and here
Udi Landau joins the lab as a research associates. Welcome Udi!
Adi Sivan joins the lab as a new MSc student. Welcome Adi!
Lior recieves a fellowship for outstanding PhD students from Milner Foundation. Congrats Lior!
Congratulationsto Anna for recieving the Excellence in research prize from the Faculty of Life Sciences!
Congratulations to Keren and Lior for recieving the Excellence in teaching prize from the Faculty of Life Sciences!
We show that the methods that infer speciation and extinction rates could be biased due to asymmetric rates of sequence evolution. Read it all here.
Machine learning can be used to select the most appropriate model for phylogeney reconstruction. Visit the ModelTeller webserver to check it out.
Model selection is considered a most basic step for phylogeny reconstruction. Here we show that this time-consuming step may be unneccessary for some phylogenetic applications
Our paper presenting the first worldwide distribution of polyploid plants is published in Nature Ecology and Evolution!
Shiran is awarded with the Edmond J. Safra Center excellent Research Student Prize
Shiran lectures at the Ernst Mayr Award Symposium, Evolution Conference, Montpellier
The OneTwoTree server is officially online. Needs to infer a phylogeny?
Itay is out for a sabbatical at China & Taiwan
CRISPys is out! Our new method can be used to design a guide RNA to target multiple members of a gene family using the CRISPR-Cas system. Read it all here
Lior Glick re-joins the lab. One day he will become a PhD student. Welcome back Lior
CRISTA is out! Our new method can better predict the cleavage efficiencies of a genomic target using CRISPR-Cas9.
Anat Shafir joins the lab as a new MSc student. Welcome Anat!
A new model that enables the detection of trait-dependent evolutionary rate shifts in sequence sites is now published in Systemtic Biology and in Nucleic Acid Research.
Keren Halabi joins the lab as an MSc student - welcome Keren!
Dana Azouri officially joins the lab as a PhD student- welcome!
Shiran Abadi receive a fellowship for outstanding PhD students from The Ariane de Rothschild Women Doctoral Program.
Gal Hyams receive the Shefler Fellowship for outstanding students awarded by Teva Pharmaceutical Industries Ltd.
We find that polyploidy occurs more often in plants that have been domesticated. Read it all here and in this News&Views
Our study on Sex determination in reptiles reveals the complex patterns by which sex determination affect lineage diversification.
Two of our studies appear in a special issue on polyploidy in the American Journal of Botany: We investigated a large number of flowering plant genera and found that polyploidy is broadly associated with sexual system dimorphism (or, dioecy). We found some phylogenetic support for the hypothesis that polyploidy instantly leads to reproductive isolation.
A new version of ConSurf was launched. See the manuscript for all details.
In our paper on sex-determining mechanism in reptiles (genetic or temperature-dependent) we suggest no effect of the sexual system on diversification patterns, rather, differences in species richness are mediated by differences in longevity and transition rates.
Itay Lecture at the Polyploidy ICPHB Conference at Croatia.
Shiran Lecture at the Genome Engineering Workshop at the Broad Institute.
Dioecy does not seems to systematically change diversification rates in flowering plants. Read it all here
Does body size infuences diversification rates? Our recent analysis in lizards and snakes found little evidence for this long standing hypothesis.
Eli Levy Karin officially joins the lab as a PhD student under a co-supervision with Prof. Tal Pupko. Welcome Eli!
Gal Hyams starts his MSc studies in the bioinformatics track
Our paper on competition and collaboration patterns among scientists is selected for faculty of 1000
What are the patterns that govern successful collaboration between researchers? Find it out in our recent paper published in PlosOne.
Mazal Tov to Gal for winning an MSc scholarships from the Manna Program in Food Safety and Security
Congratulations to Lior and Shiran for winning a prestigious prize from the Faculty of Life Sciences for their research achievements.
Anna, Lior & Itay lecture and participate at the Mechanisms of plant speciation EMBO Workshop at Sweden.
Michal Drori joins the lab as the lab programmer.
The Chromosome Counts Database (CCDB) is officially online. See the manuscript for all details.
See our reply to Soltis et al. regarding methodological aspects of studying polyploid diversification.
Our new method for the analysis of genetic population structure is published in Molecular Ecology Resources.
Menachem Darmoni joins the lab as a lab programmer.
Shiran Abadi starts her MSc studies in the bioinformatics track
Mazal Tov to Anna and Lior for winning PhD and MSc scholarships from the Manna Program in Food Safety and Security
Gal Hyams joins the lab as an undergraduate researcher. Welocme Gal.
Sex Determination: Why so many ways of doing it?
Find it out in our recent PLoS Biology paper.
Baby boom. Niv has become a father & Ayelet's third child was born.
The treeOfSex is on. A new database describing sexual systems across the tree of life is now published in Nature Scientific Data. Read it all here .
Our paper regarding new models for the evolution of chromosome numbers is now published in MBE.
It seems that polyploidy affects diversification patterns differently in fish compared to plants. Read it all here .
Our paper on patterns of chromosome-number change across the angiosperms suggests that changes by single chromosome number persist longer than whole genome duplication.
Niv recieves two (?!) post-doctoral fellwoships - from the Weiss Foundation and from the Safra Center.
Oddly, we didn't see a cake.
Change of status. Lior is starting his M.Sc studies.
Niv Sabath joins the lab as a post-doctoral fellow. Welcome to the lab Niv!
Our paper on the selective forces acting on silent sites in HIV-1 is published in BMC Evolutionary Biology.
Shiran Abadi joins the lab as a lab bioinformatician. Welcome Shiran!
Change of Status! Anna is getting married.
Yoni Mayzel joins the lab as a lab programmer.
Our lab is awarded with a two-year research grant from the SAIA Foundation.
See our review paper on the ConSurf server for predicting functional regions in proteins is now published in Isr. J. Chem.
Noa Kadmon joins the lab as a M.Sc student. She will be co-supervised by Ran Hovav from the Volcani Center.
Ayelet Salman joins the lab. Welcome Ayelet!
Naama Kopelman joins the lab as a post-doctoral fellow. Welcome Naama!
Lior Glick joins the lab. Welcome Lior!
Anna Rice joins the lab as an M.Sc. student. Welcome Anna!
Our lab is awarded a four-year research grant from the Israeli Science Foundation and an additional grant to purchase high-performance computing cluster
Moshe Einhorn joins the lab as an M.Sc. student. Welcome aboard Moshe!
Our evolutionary model that accounts for selective pressures on silent sites when inferring positive selection is now published in Molecular Biology and Evolution
Gilad Berman joins the lab as the lab technician. Welcome Gilad!
Our Science paper about the lower diversification rates of polyploid plants is selected for Faculty of 1000 biology
Our paper comparing plant growth and defense traits in weedy, domesticated, and wild sunflowers is now published in Molecular Ecology
We received our first grant! The Marie Curie Career Integration Grant is awarded for a duration of 4 years by the European Union
Tamar Eilam joins the lab as a lab administrator. Welcome to the lab Tamar!
We are officially open! The lab will be placed in a temporary location until completion of the renovation. On the agenda: grants, grants, and more grants...
Our paper about the higher extinction rates of polyploid plants is published today in Science! See the media release , blogs