PBL Sessions: Immunologic Diseases

Page 9

Further History (Sarah):

Her mother is concerned about side effects of continued medication. Does therapy need to be continued? What alternative therapies are available?

Further History (Heather):

Heather comes to see you because she has had increasing difficulty breathing for the past month. She is bothered by watery eyes and nasal congestion. On physical examination you can find nothing abnormal.

Laboratory findings (Heather): A CBC shows Hgb 15.6 g/dL, Hct 47%, MCV 91 fL, platelet count 301,500/microliter, and WBC count 8430/microliter with WBC differential count 66 segs, 2 bands, 18 lymphs, 8 monos, and 6 eos.

Use the images below to explain the pathophysiology of hypersensitivity reactions and how they apply to the persons in this family.

What

Figure 8: Image 1.

Figure 9: Image 2.

Figure 10: Image 3.

Figure 11: Image 4.

Tasks

• What can be given as an alternative therapy for Sarah?

• What do you think is Heather's diagnosis?

Stop !! Complete discussions and tasks before moving to the next page.