Hepatic Pathology, Set 5

For each of the following clinical histories, match the underlying disease process involving the liver:

1. A 50-year-old intravenous drug user has increasing jaundice. Liver function tests reveal a total bilirubin of 7.8 mg/dl, direct bilirubin of 6.7 mg/dl, AST of 330 U/L, ALT of 450 U/L, and alkaline phosphatase of 80 U/L. A liver biopsy demonstrates disruption of the limiting plate of hepatocytes around the portal triads with piecemeal necrosis:

2. While working up the cause for sudden onset of sharp right upper and lower quadrant abdominal pain in a 26-year-old woman, an abdominal ultrasound reveals the presence of a well-circumscribed 3 cm mass in the left lobe of the liver, as well as an enlarged right fallopian tube. Her HCG test is positive and ectopic pregnancy is diagnosed, even though the patient claims she has been taking oral contraceptives for 10 years:

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