Joint Pathology, Set 1

For each of the following patients, select the most likely pathologic finding:

1. A 50-year-old man with a history of urinary tract calculi has firm, palpable 1 cm nodules of the helix of the right ear and over the olecranon bursa. These nodules have been present for months:

2. A 30-year-old office worker notes pain and tingling of her right hand in the thumb and first two fingers:

3. A 40-year-old man has muscle aches and pains, along with chronic pain in both small and large joints, but without deformity or swelling. Radiographs of the hand and feet reveal no abnormal findings. Serologic tests, including antinuclear antibody, rheumatoid factor, and serologic test for syphilis (VDRL), are negative:

4. A 25-year-old man has pain, tenderness, and limitation of motion of his left knee. Arthroscopy reveals exuberant brownish nodular synovial proliferation:

5. A 52-year-old man is found to be HLA-B27 positive. He has lower back pain. A radiograph of the pelvis reveals narrowing with sclerosis of the sacroliac joints bilaterally:

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