Hepatic Pathology, Set 4

For each of the following clinical histories, match the most characteristic, diagnostic hepatic morphologic finding:

1. A 48-year-old woman who has never smoked has experienced increasing dyspnea for several years. Spirometry reveals findings characteristic for an obstructive lung disease, and a pulmonary ventilation-perfusion scan reveals decreased areas of perfusion in all lung fields, while a chest radiograph reveals increased areas of lucency in all lung fields. Her cardiac function is still normal. She has a firm liver edge on physical examination:

2. A 45-year-old woman is obese and has a history of diabetes mellitus. She uses alcohol rarely. On abdominal CT scan, the liver is slightly enlarged and shows uniform decreased attenuation. Laboratory findings show: serum total protein 7.0 g/dL, albumin 3.8 g/dL, alkaline phosphatase 62 U/L, AST 87 U/L, ALT 84 U/L, total bilirubin 1.2 mg/dL, and direct bilirubin 0.8 mg/dL:

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