Hepatic Pathology Set 1

For each of the following patients, select the most likely pathologic finding:

1. A 40-year-old healthy woman has used oral contraceptives for years. After an episode of abdominal trauma, an abdominal CT scan is performed and reveals no evidence for hematoma, but there is a 4 cm discrete mass in the right lobe of the liver:

2. A 50-year-old man has a long history of chronic alcoholism:

3. Chlorpromazine is prescribed for protracted nausea and vomiting in a 35-year-old woman. A couple of weeks later she has the abrupt onset of a fever with erythematous, pruritic skin rash, dark urine, light-colored stools, nausea, and vomiting. She notes scleral icterus. Laboratory findings include: total protein 7.7 g/dL, albumin 4.6 g/dL, alkaline phosphatase 85 U/L, AST 101 U/L, ALT 99 U/L, total bilirubin 5.5 mg/dL, and direct bilirubin 4.8 mg/dL:

4. A 5-year-old child accidentally ingests a large quantity (more than 20 g) of acetaminophen:

5. Routine halothane anesthesia is administered to a 31-year-old man undergoing appendectomy:

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A. Micronodular cirrhosis B. Acute hepatitis C. Budd-Chiari syndrome D. Intrahepatic cholestasis E. Gilbert's syndrome
F. Veno-occlusive disease G. Macronodular cirrhosis H. Primary biliary cirrhosis I. Hepatic adenoma J. Biliary atresia
K. Reye's syndrome L. Hepatocellular carcinoma M. Focal nodular hyperplasia N. Angiosarcoma O. Massive necrosis
P. Wilson's disease Q. Hemochromatosis R. Chronic hepatitis S. Sclerosing cholangitis T. AAT deficiency