Gastrointestinal Pathology, Set 3

For each of the following clinical histories, match the most closely associated gastrointestinal tract neoplasm:

1. A 39-year-old man is found to have a stool positive for occult blood. Colonoscopy reveals the presence of 10 pedunculated masses ranging in size from 0.3 to 1.2 cm in both ascennding and transverse colon. Since several members of his family have had a similar history, one of the resected masses is analyzed and found to have the presence of microsatellite instability:

2. A 38-year-old man had a positive serologic test for human immunodeÞciency virus 10 years ago. He has developed oral thrush. His CD4 lymphocyte count is now 118/microliter. He has severe nausea and vomiting. An upper endoscopy reveals a dozen gastric mucosal nodules. These nodules are 0.6 to 1.8 cm in size and are reddish purple. Microscopically they are composed of slit-like vascular spaces lined by atypical cells:

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