Gastrointestinal Pathology, Set 4

For each of the following clinical histories, match the most closely associated gastrointestinal tract neoplasm:

1. A 70-year-old man has a routine checkup with his primary care physician. The patient is found to have a stool specimen positive for occult blood. Next, a colonoscopy is performed and there is a 4 cm diameter sessile mass located at the splenic flexure 50 cm above the anal verge. The mass is resected at laparotomy and reveals elongated colonic glands lined by crowded columnar cells with hyperchromatic nuclei. This process is above the basement membrane:

2. A 63-year-old man has a 10 year history of gastroesophageal reflux disease. He has had increased difficulty with swallowing for the past 3 months. An upper endoscopy reveals an irregular area of mucosal ulceration and nodularity just above the gastroesophageal junction. No lesions are present in the stomach:

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