Gastrointestinal Pathology, Set 2

For each of the following patients, select the most likely pathologic finding:

1. A 42-year-old man on a methadone program following 20 years of intravenous drug use with heroin has the passage of bright red blood per rectum. He has no abdominal pain. Physical examination reveals active bowel sounds, no areas of tenderness, and no masses:

2. A previously healthy 50-year-old man has increasing fatigue for several months. A CBC shows WBC count 7500/microliter, Hgb 8.8 g/dL, Hct 24.2%, MCV 72 fL, and platelet count 293,000/microliter. A stool sample is positive for occult blood. Colonoscopy is performed and no abnormalities are noted:

3. A neonate was born at 30 weeks gestation. No congenital anomalies are noted. In the week following birth, the baby develops abdominal distention and has the passage of stool that is occult blood positive:

4. A 31-year-old woman is seropositive for human immunodeficiency virus. She develops yellowish-tan plaques on her tongue and oral mucosa:

5. Severe diarrhea is noted in a 45-year-old woman in hospital who has been treated with broad spectrum antibiotics for several weeks. Colonoscopy reveals patchy areas of greenish exudate overlying erythematous but non-ulcerated colonic mucosa from the rectum to the cecum:

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