Endocrine Pathology, Set 1

For each of the following patients, select the most likely pathologic finding:

1. A 42-year-old man has recently passed a urinary calculus that is composed of calcium oxalate. He has abdominal pain, and upper GI endoscopy reveals several sharply demarcated 1 cm gastric antral ulcerations. He has pain in his lower extremities:

2. An ill-defined 1 x 3 cm mass is found on surgical exploration of the neck of a 51-year-old man who was noted to have a serum calcium of 15.5 mg/dl with albumin of 4.2 g/dl and phosphorus of 2.2 mg/dL:

3. A 20-year-old woman has exhibited increased nervousness for several months. She has palpitations. She has lost 7 kg without dieting or a change in exercise patterns:

4. A 39-year-old man has a blood pressure of 160/100 mm Hg that persists for months. A serum chemistry panel shows sodium 141 mmol/L, potassium 2.8 mmol/L, chloride 101 mmol/L, CO2 25 mmol/L, glucose 90 mg/dL, creatinine 1.2 mg/dL, and urea nitrogen 15 mg/dL:

5. A 42-year-old woman has increasing malaise with fatigue. She has increasing darkness to her skin, but has not been out in the sun. Her serum cortisol is low, with no diurnal variation:

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