Endocrine Pathology, Set 2

For each of the following patients, select the most likely pathologic finding:

1. A 45-year-old woman has felt increasingly sluggish and weak for the past year. She is observed to have dry, coarse skin along with alopecia on physical examination. Serum electrolyte values are normal:

2. A neonate exhibits tetany soon after birth. The baby has a karyotype of 46, XY, 22q-:

3. A 25-year-old woman has amenorrhea along with galactorrhea, but she has never been pregnant:

4. A 25-year-old woman has failure of lactation following the birth of her third child. She was able to nurse the prior two babies without difficulty:

5. A 36-year-old man who fainted is noted to have the following laboratory findings: serum sodium 144 mmol/L, potassium 4.1 mmol/L, chloride 103 mmol/L, CO2 26 mmol/L, glucose 38 mg/dL, creatinine 1.3 mg/dL, and urea nitrogen 18 mg/dL:

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A. MEN IIa B. Sheehan's syndrome C. Parathyroid carcinoma D. Craniopharyngioma E. Islet cell adenoma
F. DeQuervain's disease G. Pheochromocytoma H. DiGeorge syndrome I. Conn's syndrome J. MEN I
K. Addison's disease L. Parathyroid hyperplasia M. Medullary carcinoma N. Iodine deficiency O. Papillary carcinoma
P. Cushing's syndrome Q. Follicular adenoma R. Prolactinoma S. Grave's disease T. Cretinism