CURRICULUM VITAE

Personal Information

Name:                           Itay Mayrose                                

Address:                        Dept. of Cell Research and Immunology, Tel-Aviv University, 69978

Tel-Aviv, Israel. Tel. 03-640-9245, Fax 03-640-2046

e-mail and homepage:     itaymay@post.tau.ac.il / http://www.tau.ac.il/~itaymay

Languages: Hebrew, English

Education

2004-2008 Ph.D. – performed under the supervision of Dr. Tal Pupko, the Department of Cell Research and Immunology, Tel-Aviv University.

· Title of Ph.D. thesis: Probabilistic algorithms for predicting functional regions in protein-coding genes.

· Ph.D. awarded with an excellence distinction.

2002-2004 M.Sc. – performed under the supervision of Prof. Dan Graur, Zoology department, Tel-Aviv University.

· Title of M.Sc. thesis: Bayesian algorithms for inferring conserved regions in proteins.

· M.Sc. graduated with summa cum laude.

1997-2001 B.Sc. – the multidisciplinary program in Computer Science and Biology, Tel-Aviv University.

· B.Sc. was graduated with summa cum laude in Biology and magna cum laude in Computer Science.

Teaching

2002-2007        Teacher assistance in the course Introduction to Bioinformatics given to graduate students in the Life Sciences Faculty, Tel-Aviv University.

2004-2007        Guest lecturer in the course Molecular Evolution given to undergraduate students in the Life Sciences Faculty, Tel-Aviv University.

Prizes and Awards

2008-                Killam Postdoctoral Fellowship, University of British Columbia, Canada

2004-2008        A scholarship for outstanding Ph.D. students awarded by the president of Tel-Aviv University

2007                 Best poster award, Safra bioinformatics retreat, Sea of Galilea, Israel

2007                 The Trotzki Foundation Prize for outstanding graduate students

2007                 Travel Award from the Ela Kodesz Institute for Cancer Research

2006                 The Anat Krauskopf Fund Travel Award

2007                 ISCB Student Travel Award

2005                 Award for excellent Ph.D. students for teaching and academic achievements

2005                 The Constantiner Institute for Molecular Genetics Travel Scholarship

2005                 Katzir-Katchalsky Student Travel Fellowship

2005                 ISCB Student Travel Award

2003                 The Wolf Foundation Prize for M.Sc. students

2000                 The Wolf Foundation Prize for undergraduate students

2000                 Award of Excellence for B.Sc students in memory of Rotenberg David

1999                 Award of Excellence for B.Sc students in memory of Moshe Avishar

1998-2000        The dean honour list (both Biology and Computer Science), Tel Aviv University

Reviewer

§ Reviewer for the journals Molecular Biology and Evolution, Bioinformatics, BMC Evolutionary Biology, and Journal of Molecular Evolution.

§ Co-reviewer for ECCB 2006 and ISMB 2007 conferences.

Publications

§ Stern A, Mayrose I, Shaul S, Gophna U, Pupko T. On the evolution of thymidine synthesis: a tale of two enzymes and a virus. Submitted.

§ Rubinstein ND, Mayrose I, Pupko T. A machine learning approach for predicting B-cell epitopes. In press.

§ Rubinstein ND, Mayrose I, Halperin D, Yekutieli D, Gershoni JM, Pupko T. 2008. Computational characterization of B-cell epitopes. Molecular Immunology. 45(12):3477-89.

§ Mayrose I, Penn O, Erez E, Rubinstein ND, Shlomi T, Tarnovitski-Freund N, Bublil EM, Ruppin E, Sharan R, Gershoni JM, Martz E, Pupko T. 2007. Pepitope: Inferring epitopes based on affinity-selected peptides. Bioinformatics. 23(23): 3244-3246.

§ Mayrose I, Doron-Faigenboim A, Bacharach E, Pupko T. 2007. Towards realistic codon models: among site variability and dependency of synonymous and nonsynonymous rates. Bioinformatics (ISMB 2007). 23: i319-i327.

*Selected for Faculty of 1000 Biology.

§ Bublil EM, Tarnovitski N, Mayrose I, Pen O, Roitburd A, Pupko T, Gershoni JM. 2007. Stepwise prediction of conformational discontinuous B-cell epitopes using the Mapitope algorithm. Proteins. 10: 294-304.

§ Mayrose I, Shlomi T, Rubinstein ND, Gershoni JM, Ruppin E, Sharan R, Pupko T. 2007. A graph-based algorithm for epitope mapping using combinatorial phage-display libraries. Nucleic Acid Research. 35: 69-78.

§ Landau M, Mayrose I, Pupko T, Ben-Tal N. 2005. ConSurf 2005: Presenting the evolutionary rate of amino acid sites on protein structures. Nucleic Acid Research. 33: W299-W302.

§ Mayrose I, Fridman N, Pupko T. 2005. A Gamma mixture model better accounts for among site rate heterogeneity. Bioinformatics (ECCB 2005). 21: Suppl 2:ii151-ii158.

§ Faigenboim DA, Stern A, Mayrose I, Bacharach E, Pupko T. 2005. Selecton: a server for detecting evolutionary forces at a single amino-acid site. Bioinformatics. 21: 2101-2103.

§ Mayrose I, Mitchell A, Pupko T. 2005. Site-specific evolutionary rate inference: taking phylogenetic uncertainty into account. J Mol Evol. 60: 345-353.

§ Mayrose I, Graur D, Ben-Tal N, Pupko T. 2004. Comparison of site-specific rate-inference methods for protein sequences: Bayesian methods are superior. Mol Biol Evol. 21: 1781-1791.

§ Weiss S, Gottfried I, Mayrose I, Xiang M, Dawson SJ, Avraham KB. 2003. Mislocalization of the POU4F3 transcription factor is a major mechanism for DFNA15 hearing loss. Mol. Cell. Biol. 23: 7957-64.

§ Pupko T, Bell RE, Mayrose I, Glaser F, Ben-Tal N. 2002. Rate4Site: an algorithmic tool for the identification of functional regions in proteins by surface mapping of evolutionary determinants within their homologues. Bioinformatics (ISMB 2002). 18 Suppl: S71-S77.

Book Chapters

§ Mayrose I and Pupko T. Probabilistic methods and rate heterogeneity. Book chapter to appear in Element of Computational Systems Biology, Wiley book series on Bioinformatics: Computational Techniques and Engineering. Lodhi H and Muggleton S. (editors). John Wiley and Sons Inc.

Abstracts

§ Mayrose I, Doron-Faigenboim A, Bacharach E, Pupko T. Towards realistic codon models: among site variability and dependency of synonymous and nonsynonymous rates. Intelligent Systems for Molecular Biology (ISMB). Vienna, Austria. July 2007. Oral presentation.

§ Mayrose I, Shlomi T, Rubinstein ND, Gershoni JM, Ruppin E, Sharan R, Pupko T. Epitope mapping using combinatorial phage-display libraries: a graph-based algorithm. European Conference on Computational Biology (ECCB). Eilat, Israel. January 2007. Poster presentation.
* This poster won the best poster award in Safra Bioinformatics Retreat, Sea of Galilea, Israel, 2007.

§ Mayrose I. Inferring protein-protein interaction sites using combinatorial phage display libraries. Predicting Function from Protein Structure Symposium. Technion, Israel. April 2007. Oral presentation.

§ Mayrose I, Pupko T. Improving among site rate variation models. Annual Meeting for the Society for Molecular Biology and Evolution (SMBE). Tempe, Arizona. May 2006. Oral presentation.         

§ Mayrose I, Fridman N, Pupko T. A Gamma mixture model better accounts for among site rate heterogeneity. Intelligent Systems for Molecular Biology (ISMB), Detroit, Michigan, June 2005. Oral presentation.

§ Mayrose I, Pupko T. Site-specific evolutionary rate inference: taking phylogenetic uncertainty into account. Mathematics of Evolution and Phylogeny Workshop, Paris, France, June 2005. Poster presentation.

Community service:

2006/7              Volunteering to help a minority student in his first year biology studies.

1995, 2001/4     A member in the SERVAS non-profit organization for world peace, goodwill, understanding and mutual tolerance.

Hobbies

Modern dance and improvisation, tai-chi, cooking, hiking.