Success! You have captured the bacterium. Following engulfment, the bacterium is contained within a phagosome, and lysosomal granules fuse with it, releasing their contents to form the phagolysosome seen here. Rapid activation of NADPH oxidase leads to generation of superoxide that is converted to hydrogen peroxide by spontaneous dismutation. Along with myeloperoxidase from the neutrophil azurophilic granules and halide ion, hydrogen peroxide is converted to HOCL that destroys the bacterium by halogenation.

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