Neovascularization with diabetic retinopathy is shown here. Note the proliferation of small vessels near the optic disk. These delicate new vessels grow toward the vitreous humor. They are prone to bleed, producing vitreal hemorrhages that obscure vision. A proliferation of fibrovascular and glial tissue ensues, and when this contracts, there is a risk for retinal detachment. [Image contributed by Nick Mamalis, MD, University of Utah]