Pulmonary Pathology, Set 3

For each of the following clinical histories, match the most closely related infectious organism involving the respiratory tract:

1. A 35-year-old HIV-positive woman presents with increasing dyspnea with non-productive cough along with fever. A chest radiograph reveals some ill-defined bilateral hilar infiltrates. She develops increasing hypoxemia. A bronchoalveolar lavage is performed, and a cytologic smear reveals small foamy bodies that on staining with Gomori methenamine silver reveal 7 micron rounded cysts with little inflammatory exudate. She recovers following trimethoprim-sulfamethoxazole therapy:

2. A 30-year-old woman has complained of a "chest cold" for the past week. She has a mild fever with headache and myalgias, but minimal non-productive cough and no hemoptysis. She has no dyspnea or orthopnea. A chest radiograph reveals pronounced interstitial infiltrates and edema. She has an elevated serum cold agglutinin titer. She improves after a course of antibiotic therapy with erythromycin:

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