Dermatopathology, Set 3

For each of the following patients, select the most likely infectious agent:

1. A 65-year-old man is undergoing chemotherapy for small cell anaplastic carcinoma of the lung. He develops an outbreak of very painful vesicles on the right side of his chest in a dermatomal distribution. He succumbs to a bronchopneumonia. At autopsy, sections of several thoracic dorsal root ganglia show neuronal destruction and loss accompanied by a mononuclear cell infiltrate:

2. A 40-year-old man has several scattered areas of skin on his arms and trunk from 0.5 to 1.6 cm in size that are slightly erythematous. Over the next two weeks, these areas become depigmented and exhibit loss of sensation to touch and pinprick. Over the next few years, he develops further loss of sensation to pain bilaterally and symmetrically in his arms and hands. Repetitive trauma results in deformity with shortening of his fingers:

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