Breast Pathology, Set 2

For each of the following patients, select the most likely pathologic finding:

1. An area of rough, scaling, exzematous skin is seen in a 1 to 2 cm diameter area overlying the right breast of a 45-year-old woman. This area has been present for months. There are no underlying palpable masses, but a mammogram reveals an irregular density with microcalcifications:

2. Following an episode of blunt trauma to the left breast of a 32-year-old woman, a firm, ill-defined 2 to 3 cm diameter lesion develops in a matter of weeks:

3. A breast "lump" in a 43-year-old woman has fibrocystic changes that include findings suggesting an increased risk for subsequent malignancy:

4. A 51-year-old woman has noted marked enlargement of her left breast over the past year. On examination there is a non-tender but firm 12 cm diameter circumscribed mass. There is no axillary lymphadenopathy. Biopsy reveals a microscopic pattern with pleomorphic, cellular stroma along with arborizing, benign appearing ducts:

5. The breasts of a 17-year-old adolescent girl are slightly enlarged, with prominent lobules and ducts filled with secretions:

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A. Intraductal papilloma B. Fibroadenoma C. Colloid carcinoma D. Phyllodes tumor E. Amastia
F. Paget's disease G. Infiltrating ductal carcinoma H. Lobular carcinoma in situ I. Fat necrosis J. Leaking silicone breast implant
K. Abscess L. Pregnancy M. Prolactinoma N. Atypical epithelial hyperplasia O. Sclerosing adenosis
P. Medullary carcinoma Q. Intraductal carcinoma R. Metastatic carcinoma S. Metaplastic carcinoma T. Gynecomastia