מנגנוני קטליזה אנזימטית (0421.3814)
MECHANISMS OF ENZYMATIC CATALYSIS
The course question: How do enzymes catalyze biochemical reactions?
Syllabus:
• The theory and principles of enzymatic catalysis
• Experimental approaches for the study of the active site
• Examples of enzymatic mechanisms: proteases, phosphatases, G proteins…
• Mechanism-based drug development
• Computer workshop – the active site
דרישות קדם: כימיה אורגנית, כימיה פיסיקלית, ביוכימיה א It is open to graduate students (Ph.D. and M.Sc. Studies) and upon approval – also to outstanding undergraduate students (third year)
נוכחות חובה
הרכב ציון:
The course includes lectures, homework, and a written exam, and it benefits 3 credit points.
מטלת סיום: בחינה בכתב
ספרות:
Structure and mechanism in protein science / Prof. Alan Fersht