Laboratory of Eye Research

Head: Dov Weinberger M.D.

Head of Research Group: Tami Livnat Ph.D.

	Tel:	972-3-9376742
	E-mail:	eyes@clalit.org.il
	Fax:	972-3-9211478

Research Topics

In vitro studies:

Blood Retina Barriers : Tight junction composition and function.

1. Interaction between RPE and endothelial cells under normal and pathological conditions.

2. The involvement of RPE and endothelial cell integrins in retinal neovascularization.

3. Effects of thrombin/ activated protein C on blood retina barrier properties and proangiogenic signals.

In vivo studies:

1. New Applications of magnetic hydrogels for retinal detachment surgeries and patching retinal breaks

2. The use of indirect diode laser as an easy to use laboratory setup for the creation of choroidal neovascularization in animal model.

3. The effect of apoE genotype on retinal neovascularization in a transgenic mice model.

4. Cross-linking of rabbit sclera using riboflavin and UVA for the prevention of progressive myopia.

Selected Publications

1. Kramer M, Dadon S, Hasanreisoglu M. Mosnelise Y, Avraham BR, Eldar I, Weinberger D, Goldenberg-Cohen N. Pro-inflammatory cytokines in a mouse model of central retinal artery occlusion. Mol Vis 15:885-894, 2009. MEDLINE

2. Dardik R, Livnat T, Nisgav Y, Weinberger D. Enhancement of angiogenic potential of endothelial cells by contact retinal pigment epithelial cells in a model simulating pathological conditions. Invest Ophthalmol Vis Sci 51 :6188-95, 2010. MEDLINE

3. Golan S, Weinberger D, Livnat T , Loewenstein A. What is the role of Ischemia in AMD? Retina Physician 9:36-40, 2012

4. Nahum Y, Barliya T, Bahar I, Livnat T, Nisgav Y, Weinberger D. Remote manipulation of posterior lamellar corneal grafts using a magnetic field. Accepted for publication. Cornea, 2013