Lab Publications

 

 

Benmocha, A., Almagor, L., Oz, S., Hirsch, J.A., and N. Dascal. (2009). “Characterization of the calmodulin-binding site in the N terminus of Ca_V1.2.” Channels, 3: . PubMed abstract

 

 

Haitin, Y., Wiener, R., Shaham, D., Peretz, A., Cohen, E.B., Shamgar, L., Pongs, O., Hirsch, J.A., and B. Attali. (2009). “Intra-cellular domains interactions and gated motions of I_KS potassium channel subunits.” EMBO J, 28: 1994. PubMed abstract

 

 

Dessau, M., Halimi, Y., Erez, T., Chomsky-Hecht, O., Chamovitz, D.A., and J. A. Hirsch. (2008). “The Arabidopsis COP9 Signalosome Subunit 7 Is a Model PCI Domain Protein with Subdomains Involved in COP9 Signalosome Assembly.” The Plant Cell, 20: 2815.  PubMed abstract

 

 

Wiener, R., Haitin, Y., Shamgar, L., Fernandez-Alonso, M.C., Martos, A., Chomsky-Hecht, O., Rivas, G., Attali, B., and J.A. Hirsch. (2008) “The KCNQ1(Kv7.1) COOH-terminus, a Multitiered Scaffold for Subunit Assembly and Protein Interaction.” J Biol. Chem, 283:5815 . PubMed abstract

 

 

Ehrlich, S., Mizrachy, L., Segev, O., Lindenboim, L., Zmira, O., Adi-Harel, S., Hirsch, J. A., Stein, R., and R. Pinkas-Kramarski. (2007). “Differential Interactions Between Beclin 1 and Bcl-2 Family Members.” Autophagy, 3: 561. PubMed abstract

 

 

Dessau, M., Chamovitz, D.A., and J. A. Hirsch. (2006). “Expression, Purification and Crystallization of a PCI domain from the COP9 signalosome subunit 7 (CSN7).” Acta Cryst. F, 62: 1138. PubMed abstract

 

 

Opatowsky, Y., Sasson, Y., Shaked, I., Ward, Y., Chomsky-Hecht, O., Litvak, Y., Selinger, Z., Kelly, K. ., and J. A. Hirsch. (2006). “Structure-function studies of the G-domain from human gem, a novel small G-protein.” FEBS Letters, 580: 5959. PubMed abstract

 

 

Shamgar, L., Ma, L., Schmitt, N., Haitin, Y., Peretz, A., Wiener, R., Hirsch, J., Pongs, O., and B. Attali. (2006). Calmodulin is essential for cardiac IKS channel gating and assembly: impaired function in long-QT mutations. Circulation Research. 98:1055. PubMed abstract

 

 

Opatowsky, Y., Chen, C-C., Campbell, K. P., and J. A. Hirsch. (2004). “Structural Analysis of the Voltage-Dependent Calcium Channel Beta Subunit Functional Core and Its Complex with the Alpha1 Interaction Domain.” Neuron, 42: 387. PubMed abstract

 

 

Opatowsky, Y., Chomsky-Hecht, O., and J. A. Hirsch. (2004). “ Expression, Purification and Crystallization of a Functional Core of the Voltage-Dependent Calcium Channel Beta Subunit.” Acta Cryst. D, 60: 1301. PubMed abstract

 

 

Opatowsky, Y., Chomsky-Hecht, O., Kang, M-G., Campbell, K. P., and J. A. Hirsch. (2003). “The Voltage-Dependent Calcium Channel Beta Subunit Contains Two Stable Interacting Domains.” J Biol. Chem., 278: 52323. PubMed abstract

 

 

Zoref-Shani, E., Bromberg, Y., Hirsch, J., Feinstein, S., Frishberg, Y., and O. Sperling. (2003). “A Novel Point Mutation (I136T) in the Conserved 5-Phosphoribosyl-1-Pyrophosphate Binding Motif of Hypoxanthine-guanine Phosphoribosyltransferase (HPRTJerusalem ) in a Patient with Kelley-Seegmiller Syndrome.” Mol. Genetics and Metabolism, 78:158. PubMed abstract

 

 

Vishnivetskiy, S. A., Hirsch J. A., Velez, M. G., Gurevich, Y. V., Gurevich, V. V. (2002). “Arrestin's transition into the active receptor-binding state requires an extended interdomain hinge." J Biol. Chem., 277:43961. PubMed abstract

 

 

Updated Sept, 2009