List of human housekeeping genes

 

Supplementary files for the paper

"Human housekeeping genes revisited"

E. Eisenberg and E.Y. Levanon, Trends in Genetics, 29 (2013)

 

List of housekeeping genes (download)

 

 

This list provided in the link above is based on analysis of next-generation sequencing (RNA-seq) data. At least one variant of these genes is expressed in all tissues uniformly; see the above paper for details. The RefSeq transcript according to which we deemed the gene 'housekeeping' is given.

 

This list replaces the older list, based on DNA-microarray data. Citation information: E. Eisenberg and E.Y. Levanon, Trends in Genetics 29, (2013).

 

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A list of housekeeping exons is also available:  Excel file - housekeeping exons . Note that the same genomic region could appear multiple times, if it belongs to multiple RefSeq transcripts.

 

Finally, we provide a small selected set of highly uniform and strongly expressed genes that may be used for experimental calibration, e.g. as PCR control genes.

Gene Name

RefSeq accession number

Gene description

Genomic coordinates (hg19) of strongly and uniformly expressed exons

C1orf43

NM_015449

chromosome 1 open reading frame 43

chr1        154192817              154192883

chr1        154186932              154187050

chr1        154186368              154186422

chr1        154184933              154185100

chr1        154184795              154184854

CHMP2A

NM_014453

charged multivesicular body protein 2A

chr19      59065411                59065579

chr19      59063625                59063805

chr19      59063421                59063552

EMC7

NM_020154

ER membrane protein complex subunit 7

chr15      34382517                34382656

chr15      34380253                34380334

chr15      34376537                34376687

GPI

NM_000175

glucose-6-phosphate isomerase

chr19      34857687                34857756

chr19      34859487                34859607

chr19      34868639                34868786

chr19      34869838                34869910

chr19      34872370                34872424

chr19      34884152                34884213

chr19      34884818                34884971

chr19      34887205                34887335

chr19      34887485                34887562

chr19      34890111                34890240

chr19      34890460                34890536

chr19      34890623                34890690

PSMB2

NM_002794

proteasome subunit, beta type, 2

chr1        36101910                36102033

chr1        36096874                36096945

chr1        36070833                36070883

PSMB4

NM_002796

proteasome subunit, beta type, 4 

chr1        151372456              151372663

chr1        151372917              151373064

chr1        151373239              151373321

chr1        151373714              151373831

RAB7A

NM_004637

member RAS oncogene family 

chr3        128525214              128525433

chr3        128526385              128526514

chr3        128532169              128532262

REEP5

NM_005669

receptor accessory protein 5 

chr5        112256859              112256953

chr5        112238076              112238215

chr5        112222711              112222880

SNRPD3

NM_004175

small nuclear ribonucleoprotein D3

chr22      24953642                24953768

chr22      24963951                24964144

VCP

NM_007126

valosin containing protein

chr9        35067887                35068060

chr9        35066671                35066814

chr9        35064150                35064282

chr9        35062213                35062347

chr9        35061999                35062135

chr9        35061573                35061686

chr9        35061011                35061176

chr9        35060797                35060920

chr9        35060309                35060522

chr9        35059489                35059798

chr9        35059060                35059216

chr9        35057372                35057527

chr9        35057116                35057219

VPS29

NM_016226

vacuolar protein sorting 29 homolog

chr12      110930800              110931036

chr12      110929812              110929927

 

 

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