| Ph.D.: |
Tel
Aviv University, 1976 |
| Phone: |
(Office)
+972-3-640-8653
(Home) +972-9-765-2388
(Fax)
+972-3-640-8653
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| E-mail: |
MichaelO@tauex.tau.ac.il
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| Room#: |
Room 409, Sherman Building |
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Personal Information
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-
Period
of Study |
Name
of University |
Subject |
Degree
or Professional Licence |
Date
of award |
| 1964-1967 |
Tel Aviv University |
Biology |
B.Sc. |
1967 |
| 1967-1969 |
Tel Aviv University |
Zoology |
M.Sc. |
1969 |
| 1969-1970 |
Department of Anatomy
School of Medicine Dundee University, Scotland
|
|
Pre-doctoral research |
|
| 1970-1976 |
Tel Aviv University |
Zoology |
Research
towards Ph.D. |
1976 |
Title of Master's Thesis:
"Embryonic development of Duvernoy's (parotid)
gland in the snakes Natrix tessellata and
Spalerosophis cliffordi (Fam. Colubridae)"
Supervisor: Prof. Elazar Kochva
Title of Doctoral Dissertation:
"The mechanism of neutralization of Vipera
palaestinae neurotoxin by a homologous serum
protein"
Supervisor: Prof. Elazar Kochva
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Selected Publications
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Borkow G. and Ovadia, M. (1992) Inhibition of Sendai
virus by various snake venoms. Life Sci., 51:1261-1267.
Borkow, G., Chaim-Matyas, A. and Ovadia, M. (1992) Binding
of cytotoxin P4 from Naja nigricollis nigricollis venom
to leukemia and melanoma cells. FEMS Microbiol. Immunol.,
105:139-146.
Chaim-Matyas, A., Borkow, G. and Ovadia, M. (1993) Encapsulation
of the cobra cytotoxin P4 in liposomes. Biotech. Appl.
Biochem., 17:31-36.
Borkow, G. and Ovadia, M. (1994) Echinhibin-1 - an inhibitor
of Sendai virus isolated from the venom of the snake
Echis coloratus. Antiviral Res., 23:161-176.
Borkow, G., Gutierrez, J.M. and Ovadia, M. (1994) A
potent antihemorrhagin in the serum of the non-poisonous
snake Natrix tessellata; isolation, characterization
and mechanism of neutralization. Biochim. Biophys. Acta,
1201:482-490.
Borkow, G., Gutierrez, J.M. and Ovadia, M. (1995) Isolation
and characterization of an effective antihemorrhagic
factor from the serum of Bothrops asper and the mechanism
of neutralization. Biochim. Biophys. Acta, 1245:232-238.
Barchan, D., Ovadia, M., Kochva, E. and Fuchs, S. (1995)
The binding site of the nicotinic acetylcholine receptor
in animal species resistant to a-bungarotoxin.
Biochemistry, 34:9172-9176.
Rappaport, D., Ovadia, M. and Shai, I. (1995) A synthetic
peptide corresponding to a conserved Heptad repeat domain
is a potent inhibitor of a Sendai virus-cell fusion:
An emerging similarity with functional domains of other
viruses. EMBO J., 14:5524-5531.
Borkow, G., Gutierrez, J.M. and Ovadia, M. (1997) Inhibition
of the hemorrhagic activity of Bothrops asper snake
venom by a novel neutralizing mixture. Toxicon, 35:865-877.
Borkow, G., Gutierrez, J.M. and Ovadia, M. (1997) Inhibition
of toxic activities of Bothrops asper and other crotalid
snake venoms by a novel mixture. Toxicol. Appl. Pharmacol.,
147:442-447.
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Students and Lab Members
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Doctoral
students
1983 - l986 Moshe Tom - The benthic phase of
the life cycle and the ovarian development of the
crustacean Parapenaeus longirostris (Decapoda,
Penaeidae) (following the death of Prof. Levinson)
1985 - 1991 Adina Chaim - The cytotoxin of Naja
nigricollis - isolation, characterization and
potential use
1989 - 1994 Sara Weissenberg - Antihemorrhagic
factors from the serum of the rattlesnake Crotalus
atrox
1989 - 1994 Gadi Borkow - Hemorrhagins of Bothrops
asper and their inhibitors
M.Sc. students
l981 - l984 Adina Chaim - Synthesis and possible role
of proteo- glycans during embryonic development of
sea urchin
l981 - l984 Raphael Kopan - Synthesis of proteoglycans
and their possible role during the development of
Volvox carteri
l981 - l984 Ora Nakar - The relationship between hemorrhagic
and proteolytic activities of snake venoms as compared
to the antihemorrhagic and antiproteolytic factors
in their blood (together with Prof. E. Kochva)
l982 - l985 Nava Levi - The possible influence of
embryonic tissues on chondrosarcoma
1987 - 1989 Gadi Borkow - Derivates of cytotoxin isolated
from the snake Naja nigricollis
1987 - 1990 Ram Reshef - Epithelial - Mesenchimal
interactions during the development of Duvernoy's
gland in snakes (together with Prof. E. Kochva)
l988 - 1991 Shai Shafir - Vittelogenesis in Parapenaeus
semisulcatus
1989 - 1992 Ofer Shenkar - The role of lipids and
lipoproteins in oocyte development of Penaeus semisulcatus
1993 - 1995 Dalia Marco - Activity of various snake
venoms on Sendai virus
1995 -
Meirav Bronstein - Inhibition of Sendai virus
by the snake serum of Crotalus atrox
1995 -
Michal Tamir - Inhibition of snake hemorrhagins
by a novel mixture of antidotes
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