Research Interests

Research in my lab centers around two topics:

1. Function of plant RAC-like GTPases in regulation of growth and development.
2. The role of protein lipid modification in plant signal transduction:
   • Subcellular targeting of Arabidopsis RAC-like GTPases.
   • Identification of Arabidopsis RACs signaling cascades.
   • Role of Arabidopsis RACs in the regulation of membrane fusion.
   • The global role of protein prenylation in plant growth and development – mutants and target proteins
   • Role of protein prenylation in ABA signal transduction.
   • CaaX processing and its role in subcellular targeting of prenylated proteins.

The Yalovsky Lab Home Page

Additional Scientific Activity:
Associate Editor - Plant Molecular Biology

Selected Publications

1. Lavy, M., Bracha-Drori, K., Sternberg, H. and Yalovsky, S. “Cell-specific prenylation independent mechanism regulates targeting of type-II RACs.” The Plant Cell, Vol 14 2002 (pp. 2431-2450)
2. Bracha-Drori, K., Lavy, M. and Yalovsky, S. “The Arabidopsis AtSTE24 is a CaaX Protease with Broad Substrate Specificity.” Journal of Biological Chemistry, Vol 277 2002 (pp 29856-29864)
3. Luan, S., Kudla, J., Manuel Rodriguez-Concepcion, M., Yalovsky, S. and Gruissem W. “CaMs and CBLs: Calcium Sensors for Specific Signal-Response Coupling in Plants.” The Plant Cell, Vol 14 Supplement 2002 (pp. S389-400)
4. Caldelari D., Sternberg, H., Rodriguez Concepcion, M., Gruissem, W. and Yalovsky, S. “Efficient prenylation by a plant geranylgeranyltransferase-I requires a functional CaaL box motif and a proximal polybasic domain.” Plant Physiology, Vol 126 2001 (pp. 1416-1429)
5. Yalovsky,S., Rodriguez Concepcion, M., Bracha K., Toledo-Ortiz, G. and Gruissem, W. "Prenylation of the floral transcription factor APETALA1 modulates its function.". The Plant Cell, Vol 12 2000 (pp. 1257-1266).
6. Yalovsky, S., Kulukian A., Rodriguez Concepcion, M., Young, C.A. and Gruissem W. “Functional requirement of plant farnesyltransferase during development in Arabidopsis.” The Plant Cell, Vol 12 2000 (pp. 1267-1278).
7. Rodriguez Concepcion, M., Toledo-Ortiz, G., Yalovsky, S., Caldelari D. and Gruissem, W. “Carboxyl methylation of prenylated calmodulin CaM53 is required for efficient plasma membrane targeting of the protein.” The Plant Journal, Vol 24 2000 (pp. 775-784).
8. Yalovsky, S., Rodriguez-Concepcion, M. and Gruissem, W. "Lipid modifications of proteins, slipping in and out of membranes". Trends in Plant Science, Vol 4 1999 (pp. 429-438)
9. Rodriguez Concepcion, M., Yalovsky, S., Fromm, H., Zick, M. and Gruissem, W. "Prenylation of a plant calmodulin determines its localization and biological function." EMBO Journal, Vol. 18 1999 (pp. 1996-2007)
10. Rodriguez-Concepcion M., Yalovsky, S. and Gruissem, W. "Protein prenylation in plants: old friends new targets". Plant Molecular Biology, Vol. 39 1999 (pp. 865-870)