Chamovitz Lab
	Publications

2009 

• Knowles, A, Koh, K, Wu, JT, Chien, CT, Chamovitz, DA, and Blau, J (2009). The COP9 Signalosome is required for light-dependent TIM degradation and Drosophila clock resetting. Journal of Neuroscience (in press).

2008

• Dessau, M, Halimi, Y, Erez, T, Chomsky-Hecht, O, Chamovitz, DA, and Hirsch, JA (2008). The Arabidopsis COP9 Signalosome Subunit 7 Is a Model PCI Domain Protein with Subdomains Involved in COP9 Signalosome Assembly. Plant Cell, 20, 2815-2834.
• Halimi, Y and Chamovitz, DA (2008) An Introduction to the PCI Complexes and the Ubiquitin Proteasome System (UPS) in Plant Development. In: Intracellular Signaling in Plants, Z. Yang, Ed. Oxford, Blackwell Publishing, (pp. 273-305).
• Caspi, N, Levin, I, Chamovitz, DA and M. Reuveni. (2008) A mutation in the tomato DDB1 gene affects cell and chloroplast compartment size and CDT1 transcript. Plant Signal Behav. 3, 641-649.
• Paz-Aviram, T, Yahalom, A and Chamovitz, DA (2008) Arabidopsis eIF3e interacts with subunits of the ribosome, Cop9 signalosome and proteasome. Plant Signal Behav 3: 409-411.
• Rencus-Lazar, S, Amir Y, Wu, J-T, Chien, C-T, Chamovitz, DA, and Segal, D (2008) The proto-oncogene Int6 is essential for neddylation of Cul1 and Cul3. PLoSOne, 3(5): e2239.
• Oren-Giladi, P, Krieger, O, Edgar, BA, Chamovitz, DA, and Segal, D (2008) Cop9 signalosome subunit 8 (CSN8) is essential for Drosophila development. Genes to Cells 13: 221-231. 
• Yahalom, A, Kim, TH, Roy, B, Singer, R, von Arnim, AG and Chamovitz, DA (2008) Arabidopsis eIF3e is regulated by the COP9 signalosome and has an impact on development and protein translation. Plant J, 53: 300-311.

2007

• Oron, E, Tuller, T, Li, L, Rozovsky, N, Yekutieli, D, Rencus-Lavar, S, Segal, D, Chor, B, Edgar, BA and Chamovitz, DA  (2007) Genomic analysis of COP9 signalosome function in Drosophila melanogaster reveals a role in temporal regulation of gene expression. Mol Sys Biol 3:108.
• Harari-Steinberg, O, Cantera, R, Denti, S, Bianchi, E, Oron, E, Segal, D and Chamovitz, DA. (2007)  COP9 Signalosome subunit 5 (CSN5/Jab1) regulates the development of the Drosophila immune system: effects on Cactus, Dorsal and hematopoiesis. Genes to Cells 12: 183-195. 

2006

• Dessau, M, Chamovitz, DA and Hirsch, JA  (2006) Expression, purification and crystallization of a PCI domain from the COP9 signalosome subunit 7 (CSN7). Acta Crystallogr D Biol Crystallogr. 62:1138-40.
• Malec, P. and Chamovitz, D.A. (2006) Characterization and Purification of Kinase Activities against Arabidopsis COP9  Signalosome Subunit 7. Israel Journal of Chemistry 46: 239-246.

2005

• Tuller, T. Oron, E, Makavy, E, Chamovitz, DA, and Chor, B. (2005) Time-Window Analysis of Developmental Gene Expression Data with Multiple Genetic Backgrounds. In: Algorithms in Bioinformatics, R. Casadio, and G. Myers, eds. Berlin, Springer Verlag, 2005 (pp. 53-64).
• Gemmill, RM, Lee, J, Chamovitz, DA, Segal, D, Hooper, JE and Drabkin, HA (2005) Growth suppression induced by the TRC8 hereditary kidney cancer gene is dependent upon JAB1/CSN5. Oncogene 24, 3503-11.

2004

• Kim, TH, Kim, B-H, Yahalom, A, Chamovitz, DA and von Arnim, A.G.  (2004) Translational regulation via 5' mRNA leader sequences revealed by mutational analysis of the Arabidopsis translation initiation factor subunit eIF3h Plant Cell 16: 3341-56.
• Harari-Steinberg O., and Chamovitz DA (2004) The COP9 signalosome: mediating between kinase signaling and protein degradation Curr Protein Peptide Sci. 5: 185-189.

2003

• Chamovitz, DA and Yahalom, A (2003) A systems approach to the COP9 signalosome Plant Physiol 132: 426-427. 
• von Arnim, A.G. and Chamovitz, D.A. (2003) Protein homeostasis: A degrading role for INT6/eIF3 Curr Biol 13: R323-R325.

2002

• Oron, E, Mannervik, M, Rencus, S, Harari-Steinberg, O, Neuman-Silberberg, FS, Segal, D and Chamovitz, DA. (2002) COP9 signalosome subunits 4 and 5 regulate multiple pleiotropic pathways in Drosophila melanogaster Development 129: 4399-4409. 
• Chamovitz, D.A., Glickman, M. (2002) The COP9 Signalosome Curr Biol 12: R232.
• Yahalom, Y. and Chamovitz, D.A. (2002) ). Expression of recombinant proteins. In: Molecular Plant Biology: A Practical Approach. Eds: P. Gilmartin and C. Bowler. (Oxford: Oxford University Press). pp. 111-122.
• Malec, P, Yahalom, A and Chamovitz, DA. (2002) Identification of a light-regulated protein kinase activity from seedlings of Arabidopsis thaliana Photochem Photobiol 75: 178-183.
• Suh, GSB, Poeck, B, Chouard, T, Oron, E, Segal, D, Chamovitz, DA and Zipursky, SL. (2002) Drosophila JAB1/CSN5 acts in photoreceptor cells to induce glial cells Neuron 33: 35-46.

2001

• Harari-Stienberg, O, Ohad I, and Chamovitz DA (2001) Dissection of the light signal transduction pathways regulating the two Early light induced protein genes in Arabidopsis. Plant Physiol 127: 986-97.
• Kim, T-H, Hofmann, K, von Arnim, AG and Chamovitz, DA(2001) The PCI complexes: pretty complex interactions in diverse signaling pathways Trends Plant Sci 6: 379-386.
• Chamovitz, DA and Segal, D (2001) JAB1/CSN5 and the COP9 signalosome. A complex situation EMBO Rep. 2: 96-101
• Yahalom, A, Kim, TH, Winter, E, Karniol, B, von Arnim, AG and Chamovitz, DA (2001) Arabidopsis eIF3e (INT6) associates with both eIF3c and the COP9 signalosome subunit CSN7 J Biol Chem 276: 334-40.

2000

• Karniol, B and Chamovitz, DA (2000) The COP9 signalosome: From light signaling to general developmental regulation and back. Curr Opin Plant Biol 3: 387-93.
• Deng, XW, Dubiel, W, Wei, N, Hofmann, K, Mundt, K, Colicelli, J, Kato, J, Naumann, M, Segal, D, Seeger, M, Carr, A, Glickman, M and Chamovitz, DA. (2000) Unified nomenclature for the COP9 signalosome and its subunits: an essential regulator of development Trends Genet 16: 202-3.

1999

• Freilich, S, Oron, E, Kapp, Y, Nevo-Caspi, Y, Orgad, S, Segal, D and Chamovitz, DA. (1999)  The COP9 signalosome is essential for development of Drosophila melanogaster Curr Biol 9: 1187-90.
• Karniol, B, Malec, P and Chamovoitz DA (1999) Arabidopsis FUSCA5 Encodes a Novel Phosphoprotein That Is a Component of the COP9 Complex Plant Cell 11: 839-848.

1998

• Karniol, B, Yahalom, A, Kwok, S, Tsuge, T, Matsui, M, Deng, XW and Chamovitz, DA.  (1998)  The Arabidopsis homologue of an eIF3 complex subunit associates with the COP9 Complex. FEBS Lett 439: 173-9.
• Chamovitz, DA and Deng, X-W (1998) Molecular Approaches to Biochemical Purification: The COP9 Complex Paradigm In: Cellular Integration of Signaling Pathways in Plant Development. Eds: F. Lo Schiavo, R. L. Last, G. Morelli and N. V. Raikhel. (Berlin: Springer-Verlag). pp. 83-91.

1997

• Moscovici-Kadouri, S and Chamovitz, DA (1997) Characterization of a cDNA encoding the Early Light-Inducible Protein (ELIP) (Accession No. U89014) from Arabidopsis. Plant Physiol 115: 1287.
• Chamovitz, D.A. and Deng, X.-W. (1997) The COP9 Complex: A link between photomorphogenesis and general developmental regulation? Plant Cell Environ 20: 734-39.

< 1997

• Chamovitz, D.A. and Deng, X.-W. (1996) Light Signaling in Plants Crit Rev Plant Sci 15: 455-78.
• Chamovitz, DA, Wei, N, Osterlund, MT, von Arnim, AG, Staub, JM, Matsui, M and Deng, XW(1996) The COP9 Complex, a Novel Multisubunit Nuclear Regulator Involved in Light Control of a Plant Developmental Switch Cell 86: 115-21.
• Chamovitz, DA and Deng, X-W (1995) The novel components of the Arabidopsis light signaling pathway may define a group of general developmental regulators shared by both animal and plant kingdoms. Cell 82: 353-4.
• Wei, N, Chamovitz, DA and Deng, X-W (1994) Arabidopsis COP9 is a component of a novel signaling complex mediating light control of development. Cell 78: 117-24.

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